JIANG Lab & Research Group

Research

Project 1

Stem Cells and Translational Medicine

Ministry of Science and Technology (MOST) of China, National Key R&D Program of China, Young Scientist Scheme, 2019YFA0111900, 2019 to 2023.

Tissue Specific Stem/Progenitor Cells in Cartilage Regeneration

  • J Ortho Transl, 2(2):56-65 (2014)
  • Stem Cells Transl Med, 5(6): 733–44(2016)
  • Bioact Mater. 25:256-272 (2023)
  • Stem Cell Res Ther, 14:160 (2023)
 Disease Activated Stem/Progenitor Cells in Osteoarthritis

  • Nature Reviews Rheumatology, 11(4):206-12 (2015)
  • Arthritis Research & Therapy, 17;17:327 (2015)
  • Osteoarthritis and Cartilage, 25(1), 138-145 (2017)
  • The FASEB Journal, 33(9):10231-10239 (2019)
  • Frontin Cell &Dev Biol (2021)
Project 2

Application of tissue-specific stem/progenitor cells for osteoarthritis

ITC -Health@InnoHK -The Center for Neuromusculoskeletal Restorative Medicine (CNRM), co-PI, 2022 to 2027, ITC.  https://www.cnrm.com.hk/

       

Use mouse model to study osteoarthritis progression. This is a u CT reconstruction picture to show the bone changes of mice knees in healthy and OA joints. White arrows show the disease changes in osteoarthritic knee joints. (Credit: Jiang Lab RM, http://jianglabrm.com)

  • Bioact Mater. 25:256-272 (2023)
  • Stem Cell Res Ther, 14:160 (2023)
  • PLoS ONE,18(10): e0286626 (2023)
Project 3

Meniscus Regeneration via Activation of Human Tissue Resident Stem Progenitor Cells

RGC – General Research Fund, No.14104022, 2023 to 2026.

(Credit: Jiang Lab RM, http://jianglabrm.com)

  • Bioact Mater. 25:256-272 (2023)
Project 4

Grancalcin+ Immune Cells in Osteoarthritis: Cellular and Molecular Targets for Future Intervention

NSFC/RGC Joint Research Scheme, NSFC/RGC: N_CUHK483/22, UGC, Hong Kong SAR, 2023-2027

  • PLoS ONE, 18(10): e0286626 (2023)
  • Bone Res, Jan 25;12(1):6 (2024)
Research Interests and Expertise in
  • Tissue Engineering and Regenerative Medicine
  • Cartilage and Bone Repair and Regeneration
  • Adult Tissue Specific Stem/Progenitor Cells
  • Regulating Stem Cells for Cell-based Therapy
  • Regulators of Stem Cell Aging
  • Mechanism of Osteoarthritis and Other Degenerative and Inflammatory Diseases
  • Bioproducts for Cell-based Therapy
  • From Bench to Bedside and to the Bench – the Pathway of Translational Medicine
Supported by
  • The Chinese University of Hong Kong
  • Ministry of Science and Technology (MOST) of China, National Key R&D Program of China
  • Innovation and Technology Commission, Health@InnoHK, Hong Kong SAR, China
  • University Grants Committee, Hong Kong SAR, China
  • National Natural Science Foundation of China